Switching mice from a high glycemic diet to a low glycemic diet stopped the development of certain signs of age-related macular degeneration.
The findings reveal insights into the impact of diet, metabolic changes, and the gut microbiome on macular degeneration.
“Our findings show an interaction between dietary carbohydrates, the gut microbiome, specific biochemical molecules, and AMD features. This work should lead to new approaches to understand, diagnose, and treat early AMD—perhaps before it affects vision,” Taylor explains. “Already anticipated by our human epidemiologic studies, the findings imply that we can optimize nutrition to prevent the progression of AMD.”