• 2019 Senior Report Senior Report: Older Americans have more options for home care, but still struggling.

    The United Health Foundation has released results of a sweeping new study benchmarking the health of older adults. The America's Health Rankings® Senior Report was created in partnership with GAPNA to improve the health of America's seniors.

    The data will help advanced practice nurses and other providers deliver quality care.

    Find out about it!

  • 38th Annual GAPNA Conference

    October 3-5, 2019 at the Paris Hotel, Las Vegas, NV.

    Focused education; lasting connections, networking, free access to the GAPNA Online Library.

    Earn up to 22 contact hours (including pre-conference workshops).

    Get more information and register now!

  • AwardCall for Excellence Award Nominations

    The awards are: Emerging Chapter Award, Established Chapter Excellence Award, Special Interest Group Excellence Award, Excellence in Clinical Practice Award, Excellence in Community Service Award, Excellence in Education Award, Excellence in Leadership Award, and Excellence in Research Award.

    The nominations are tallied in July and the winners are announced every year during the Awards Celebration at the GAPNA Annual Conference.

    Now is the time to nominate a colleague or yourself - DEADLINE is June 1, 2019.

    Get started... nominate today!

  • FREE continuing education credit is available for the following session:

    "Contemporary Heart Failure Management"

    (session captured at the GAPNA 2018 Annual Conference)

    For May/June 2019 - Get Your Free CNE Now!

  • AwardNew for GAPNA members: MCM Education

    GAPNA has partnered with a MCM Education to offer a series of CNE programs available to GAPNA members. "Alzheimer’s Disease Today and Tomorrow: Optimal Treatment and Collaborative Care," is the first program offered.

    What are the state-of-the-art strategies for managing the symptoms of Alzheimer’s disease? How can the multidisciplinary team work together to ensure timely intervention and optimal outcomes?

    Find out about it!

  • Meet the Candidates for the 2019-2020 BOD!
    The time to vote is right now: May 6 - 31, 2019!

    Please take a moment to read about this year’s candidates and why they feel they should be chosen for the position noted.


Combating Cognitive Decline

Could Boosting Lymphatic Function Combat Age-Related Cognitive Decline?

Scientists only recently discovered lymphatic vessels in the brain that remove cellular debris and other waste. Now, new research published in Nature on July 25, 2018, suggests these vessels could play a role in age-related cognitive decline and Alzheimer’s disease.

Researchers from the University of Virginia, Charlottesville, studied the performance of lymphatic vessels in the brains of mice and the drainage of cerebral spinal fluid (CSF) from blood vessels into the lymph nodes – also known as the brain’s waste-removal system.

Using methods that impaired the function of the lymphatic vessels in younger mice resulted in decreased drainage of large molecules from CSF into lymph nodes, reduced flow of CSF in certain areas of the brain involved in learning and memory, and reduced spatial learning and memory abilities.

Researchers compared the function of lymphatic vessels in younger and older mice. They found that in older mice, lymphatic vessels were narrower, and large molecules did not drain out of the CSF into the lymph nodes as well. Using a method to boost lymphatic function in older mice resulted in improved cognitive function.

Researchers also found that impairing brain lymphatic vessels in mouse models of Alzheimer’s disease led to higher levels of amyloid-beta deposits in the tissue covering the brain as the mice aged. Abnormal buildup of the protein amyloid-beta is a factor in Alzheimer’s disease. The researchers’ findings in the mouse models were mirrored in postmortem analysis on the brains of nine people who had Alzheimer’s disease.

According to the researchers, determining whether altering lymphatic vessels in people would have similar benefit to what was seen in the mouse models requires further study, but these initial findings could point to a new possible target for preventing or delaying age-related cognitive decline and Alzheimer’s disease.

For details, see Da Mesquita et al. (2018). Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease. Nature, 560(7717), 185-191.

Join your friends at the 2019 Contemporary Pharmacology and Prescribing in Older Adults Conference, March 28-30, 2019, in Chicago, IL.

Register today!